Peptide-Guide
How to use Research Peptides

Bremelanotide (PT-141)

Bremelanotide PT-141 Dose:

Light:  .5mg
Common:  1mg
Large:  2mg

Bremelanotide (PT-141) was developed from Melanotan 2 (MT-II).  PT-141 is a metabolite of MT-II that lacks the C-terminal amide function-stripping away tanning properties.  

PT-141:  Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH

Treatment:  Studies have shown bremelanotide to be effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder).  PT-141 is the only synthetic aphrodisiac.  Unlike Viagra and other related medications (PDE5s), PT-141 does not act upon the vascular system, but directly through the nervous system (hypothalamus) to increase desire.  Treatment with PDE5 inhibitors and PT-141 are known to have a synergistic effect.

Feel the Desire:  Bremelanotide is a melanocortin peptide hormone.  PT-141 binds to the melanocortin 4 receptor (MC4R) in particular.  Nine out of ten volunteers experienced sexual arousal in trials.  The aphrodisiac effects of Bremelanotide are in a class of its own. 

Men's Journal Magazine:
  "...it took hold. I felt a great surge of affection (greater than any regular level of arousal). My body tingled and I developed an erection that wouldn’t quit. For two hours the drug wouldn’t let me out of its grasp — nor my wife out of mine." -Frederick Kaufman

Mens Journal Magazine September 2009 The Sex Drug that Really Works

Females:
  Women who took part in trials said that they felt a "tingling and a throbbing" along with "a strong desire to have sex."  An initial flush occurs post injection, followed by nausea which is dose dependent.  For most, effects generally do not take place until a couple hours post injection, peaking around the four hour mark.   
Men said PT-141 made them feel "younger and more energetic" as well as sexually interested and aroused. "You're ready to take your pants off and go," said user "a drug that makes you not only able to but eager to."

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10mg and 2mg PT-141 samplesBremelanotide PT-141 Peptide:  Bremelanotide comes in 10mg and 2mg vial sizes.  Peptides photographed at right are synthesized by the same laboratory, contain no filler and therefore the difference is visible.  Freeze dried Melanotan peptides (PT-141) are very durable and stable.  Most PT-141 comes in the industry standard 10mg size.  The 2mg PT-141 is used more as a travel peptide or couples dose.  As a lifestyle peptide, the 10mg product is a lot to consume and may offer up to 20 doses when dosing light.  The PT-141 peptide reconstituted with bacteriostatic water remains potent in the fridge for months.  Nasal sprays, pre-mixed PT-141, pills and loose powder are not legitimate.  There are successful reports of snorting and nasal spray experiences...however they are few and far between.

Window of Opportunity:  Bremelanotide, injected (subcutaneously), has a unique window of opportunity lasting six to 72 hours.  In lab trials female rats exposed to PT-141 began "flirting" with male rats for sex. Postures and movements left no doubt in the male rats minds that they were in the mood.  The human PT-141 date is one where the dosage precedes the activity by at least a couple hours.  When the stars align, hours after the injection, ...this is your window of opportunity, enjoy.

Reconstitute and use PT-141 for Research:



Mixing:  Bacteriostatic water is used for reconstitution. 

Example-  1ml(cc) bacteriostatic water per 10mg PT-141 vial equates to a 1mg dose approximately each 10 units on a U100 insulin syringe.
Example-  1ml(cc) bacteriostatic water per 2mg PT-141 vial equates to a 1mg dose approximately every 50 units on a U100 insulin syringe.

Recommended strategy for mixing and dosing would be to reconstitute with the volume that yields a .1ml injection. 

Example-  1ml(cc) bacteriostatic water per 10mg PT-141 vial equates to a 1mg dose approximately each 10 units on a U100 insulin syringe.
Example-  .2ml(cc) bacteriostatic water per 2mg PT-141 vial equates to a 1mg dose approximately every 10 units on a U100 insulin syringe.

Dosing:  Read as much as possible to gain clarity and align expectations.  Gradually dosing increases likelihood for success without sides.  A test dose of .25-.5mg on the first attempt is recommended.  1mg, give or take a quarter, is the efficacious dose which yields the most hero stories reported by users.

Buy PT-141:

Buy Tan Research PT-141

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